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NIR Inspection

Near-Infrared Spectroscopy for Controlled Release Tablets

Confirming the integrity of an osmotic drug delivery system has been simplified with the addition of NIR spectroscopy to Ackley’s line of pharmaceutical tablet laser drilling machines.

The osmotic drug delivery system is an advanced timed release mechanism usually in the form of a bi-layer tablet with a semi-permeable outer membrane which retains its integrity until it reaches the intestines. If this coating is damaged, the drug might release immediately after ingestion, which could be very harmful, or even fatal, to the consumer.

NIR Inspection provides a quick and accurate way to verify that a tablet’s enteric coating is acceptable and therefore safe for consumption. Near-infrared spectroscopy provides a unique advantage for pharmaceutical manufacturers due to its ease of use and fast, accurate analysis of solid dosage forms. This analytical technique uses the near-infrared region of the electromagnetic spectrum to provide a material signature that can be plotted to show peaks at specific wavelengths of light. This analysis provides information on a material’s composition and can provide important information about the safety and quality of coatings on OROS tablets.

Ackley’s CO2 precision laser drilling machinery is now equipped with optional near-infrared spectroscopy in addition to vision inspection. Our Class 1 Laser tablet drilling machines drill sub-millimeter sized apertures into the enteric coating of single and bi-layer tablets to achieve the desired dissolution rate and drug release profile. This fully-integrated NIR inspection system provides and increased level of safety for consumers and additional peace of mind for pharmaceutical manufacturers by giving them twice the inspection power, ensuring that only the best products make it to market.

Whatever your laser drilling needs, our engineering team is ready to design a solution that will give your controlled release product a perfectly aligned, precisely drilled aperture, each and every time.

  • NIR Inspection Osmotic Drug Delivery System Tablet Spill
  • Laser Drilling with NIR & Vision Inspection for Osmotic Drug Delivery System
  • Ackley VIP Laser Drilling Machine with Near Infrared Inspection
  • Ackley Tablet Samples 07
  • Ackley Laser Drilling Tablet Samples 03
  • Ackley Tablet Samples 08
  • Ackley Laser Drilling Tablet Samples 01

How an Osmotic Drug Delivery System Works

How Osmotic Drug Delivery Works Infographic

Did You Know?

Ackley uses the same NIR Spectrometers used by NASA in their mission to find water on the Moon.

Ackley Machine Corporation is at the forefront of cutting-edge pharmaceutical equipment manufacturing. Our VIP Laser Drill + NIR features two fully-integrated Brimrose AOTF-NIR Spectrometers, delivering fast-responding analysis of a tablet’s enteric coating. This process ensures the integrity of each osmotic controlled release pharmaceutical product prior to laser drilling. This innovative use of near-infrared technology improves OROS production quality and consistency. (Photo courtesy of Brimrose)


NIR Inspection Resources

Pharmaceutical Laser Drilling with NIR Inspection Whitepaper Cover

Pharmaceutical Laser Drilling with NIR Inspection

From sugar coatings to film and gel coatings, many types of outer coatings make tablets easier to swallow and protect from light and moisture infiltration. However, osmotic-controlled release oral delivery ...
Get the Whitepaper
VIP Laser Drill + NIR Machine

Ask an Expert: Near-infrared Inspection Systems

Learn what a near-infrared inspection (NIR) system is, how it works and what its benefits are for the pharmaceutical manufacturing industry ...
Read the Article

Laser Drilling Machines

VIP Laser Drill + NIR Machine
CO2 Laser NIR Inspection Production R & D Vision Inspection

VIP Laser Drill + NIR

Drill & Inspect
View

Get a FREE Product Evaluation

Need help figuring out the best machine for your product?

With a little information we can evaluate your product and help guide you to the right machine for printing, marking or laser drilling on your blank tablets and capsules.


Other Capabilities

Seamless Laser Marking

Seamless Laser Marking

Ackley Capabilities - Laser Drilling Featured Image

Laser Drilling

Laser Marking Capabilities Featured Image

Laser Marking

Solid Dose Printing and Laser Marking

Capsule & Tablet Printing

Confectionery Printing

Confectionery Printing

NIR Inspection Osmotic Drug Delivery System Tablet Spill

NIR Inspection

Vision Inspection

Vision Inspection

Confectionery Printing

Printed Confectionery Machines for Perfectly Branded Candy

At Ackley, we understand the unique challenges and solutions confectionery manufacturers need from their ink and/or laser printing systems. The shape and size of your candy as well as achieving the proper consistency of the edible ink will play a role in your results. Your branded candy needs clear, precise brand imprinting that will set you apart from the competition without slowing down your production line.

We provide solutions for all types of confectionery–from gumballs to jelly beans, chocolate lentils to gummies, stick gums, hard-shelled candies and everything in between. Our skilled engineers will work with you to design a system that will create a precise mark on your product, time after time, at output rates that are at the top of the industry.

Whether you need ancillary machines to sort candy tablets or machine vision inspection to ensure print quality, our team of experts can design solutions to print or laser mark on virtually any sized or shaped confection, offering unlimited opportunities for brand expression.

  • Confectionery Printing Gum Carousel 01
  • Confectionery Printing Chocolate Covered Candies Carousel 02
  • Printed Candy Carousel 03
  • Confectionery Printing Candy Carousel 04
  • Confectionery Printing Carousel 05
  • Candy Carousel 05

Here’s a Fun Fact

Our machines can ink or laser print jelly beans, candy-coated chocolates, and even foil-wrapped sweets!

Does your confectionery product require printing perfection?

Our patented Vision Inspection with Single Product Rejection can inspect for:

  • Print registration
  • Incomplete printing
  • Faded or blurry printing
  • Double printing
  • Chipped, capped or broken product
  • Coating defects
  • Stains or specks
  • Foreign object or rogue product removal


Confectionery Printing Resources

Pharmaceutical Ink

Characteristics of Confectionery and Pharmaceutical Ink

Selecting which edible printing ink to use for your product should involve careful consideration. A number of solvent and aqueous ink variations are available to print onto the surface of ...
Read the Article
Tablet Printing Machine Evolution - A Brief History from Walnuts to Capsules

The Curious Evolution of the Tablet Printing Machine

You probably know that the tiny print on medicines is meant to help doctors, patients and pharmacists recognize which drug is which. But have you ever wondered about how that ...
Read the Article

Confectionery Printing Machines

Adjustable Angle Ramp Tablet Printing Machine
Production Vision Inspection

Adjustable Angle Ramp Printer

Print and Inspect
View
Tablet Printing Machine VIP Printer
Production R & D Vision Inspection

VIP Printer

Print and Inspect
View
Cantilever Ramp Capsule Printing Machine
Production Vision Inspection

Cantilever Ramp Tablet and Capsule Printer

Print and Inspect
View
Drum Laser Marking Machine
Production Vision Inspection

Servo Drum Printer

Print and Inspect
View

Get a FREE Product Evaluation

Need help figuring out the best machine for your product?

With a little information we can evaluate your product and help guide you to the right machine for printing, marking or laser drilling on your blank tablets and capsules.


Other Capabilities

Seamless Laser Marking

Seamless Laser Marking

Ackley Capabilities - Laser Drilling Featured Image

Laser Drilling

Laser Marking Capabilities Featured Image

Laser Marking

Solid Dose Printing and Laser Marking

Capsule & Tablet Printing

Confectionery Printing

Confectionery Printing

NIR Inspection Osmotic Drug Delivery System Tablet Spill

NIR Inspection

Vision Inspection

Vision Inspection

Capsule & Tablet Printing

Capsule & Tablet Printing Machines with Optional Vision Inspection

We offer pharmaceutical printing systems for tablets, capsules and softgels of every shape and size. Our machines can print on one or both sides of a product and in one or multiple colors.  What you can print is limited only by your imagination and the size of the available printing area.

We print using rotogravure offset printing for optimum print quality at high output rates and offer inkjet tablet printing machines for products requiring non-contact marking. Our patented positioning technology ensures that your logo, brand name, dosage or other information is presented with unparalleled accuracy and precision, time after time.  Our patented vision inspection systems with single tablet rejection inspect and ensure that only the best of your products make it to market.

Whatever your printing needs, from R&D through full scale production, Ackley’s team of experienced engineers will customize a solution to provide the high quality printing your brand deserves.

  • Tablet Printing Spill 01
  • Tablet Printing Spill 02
  • Tablet Printing 03
  • Tablet Spill 04
  • Printed Tablets 05
  • Printed Tablets 06
  • Printed Tablets 07
  • Printed Tablets 08
  • Printed Tablets 09
  • Printed Tablets 10

Compliance

We adhere to or surpass the strictest regulations set forth by the Food and Drug Administration (FDA) and their approach to Current Good Manufacturing Practice (CGMP) regulations.

  • FDA 21 CFR Part 11 Compliant
  • cGMP Design
  • OPC-UA Data Compliant
  • CE Compliant
  • Validation Package Available

Pharmaceutical Capsule & Tablet Printing Machines

Adjustable Angle Ramp Tablet Printing Machine
Production Vision Inspection

Adjustable Angle Ramp Printer

Print and Inspect
View
Tablet Printing Machine VIP Printer
Production R & D Vision Inspection

VIP Printer

Print and Inspect
View
Cantilever Ramp Capsule Printing Machine
Production Vision Inspection

Cantilever Ramp Tablet and Capsule Printer

Print and Inspect
View
Drum Laser Marking Machine
Production Vision Inspection

Servo Drum Printer

Print and Inspect
View

Get a FREE Product Evaluation

Need help figuring out the best machine for your product?

With a little information we can evaluate your product and help guide you to the right machine for printing, marking or laser drilling on your blank tablets and capsules.


Our ongoing relationship with Ackley is fantastic. I go and see them at every trade show I go to.

– Darren Lawson, Packaging & Operations Manager, Surepharm

Capsule & Tablet Printing Resources

The Evolution of the Printed Tablet & Capsule Whitepaper Cover

The Evolution of the Printed Tablet & Capsule

If you have ever dropped a tablet on the floor or mixed several pills of similar color together in a pill box, you understand how important it is to be ...
Get the Whitepaper
Solid Dose Printing and Laser Marking

Ask an Expert: Applying Identification to Solid Dosage Drug Products

Learn the benefits and drawbacks of on-dose marking methods for solid dosage drug products—ink printing and CO2 / UV laser marking ...
Read the Article
Pharmaceutical Ink

Characteristics of Confectionery and Pharmaceutical Ink

Selecting which edible printing ink to use for your product should involve careful consideration. A number of solvent and aqueous ink variations are available to print onto the surface of ...
Read the Article
Tablet and Capsule Cantilever Ramp Printer Detail

Surepharm Invests in On-Dose Printer for Sugar-Coated Tablet

Recently, Surepharm received an inquiry about manufacturing a product for the European market. The product was a sugar-coated tablet with a volume of about 23 million tablets per year. The ...
Read the Case Study

Other Capabilities

Seamless Laser Marking

Seamless Laser Marking

Ackley Capabilities - Laser Drilling Featured Image

Laser Drilling

Laser Marking Capabilities Featured Image

Laser Marking

Solid Dose Printing and Laser Marking

Capsule & Tablet Printing

Confectionery Printing

Confectionery Printing

NIR Inspection Osmotic Drug Delivery System Tablet Spill

NIR Inspection

Vision Inspection

Vision Inspection

Laser Marking

CO2, Green & UV Laser Marking Machines for Pharmaceutical Tablets and Capsules

Also referred to as laser printing, laser writing and laser etching, the laser marking of logos, branding and product codes onto tablets and capsules is critical to brand recognition. It also serves as a deterrent to counterfeiting and pharmacy dispensing errors. Serving the world’s top companies, Ackley has been designing and manufacturing innovative machines for laser marking for pharmaceutical industry products, as well as nutraceuticals, for over 40 years. Our CO2, Green and UV tablet and capsule laser marking machines provide high-quality precision marking in a compact footprint with an emphasis on safety and ease of use. 

All laser marking machines come equipped with custom carrier bars or links so that each tablet or capsule will rest in the perfect position for accurate laser marking. To ensure operator and workplace safety, Ackley machines use Class 1 Laser systems.

Your needs and product type will determine which laser system is best suited for you. Our skilled team of expert engineers is ready to put their experience to work for your brand. Whether you are looking to laser etch into the outer coating of softgels with CO2, laser mark onto the outer coating of tablets with UV, or have a sensitive surface suited for green laser marking, let Ackley customize a laser marking solution to make your product look its absolute best.

  • Laser Marking Softgel Sample 01
  • Laser Marking for Pharmaceutical Industry Products Sample 02
  • Candy Sample 03
  • Etching Pharmaceuticals With a Laser Softgel Sample 04
  • Softgel Sample 05
  • Laser Marking Capabilities Featured Image


Available with Three Types of Lasers

Output Rates from 50,000 to 500,000 / hour

To find out which one is right for your product, talk to our sales team.

CO2 capsule sample of laser marking for pharmaceutical industry products
Ackley CO2 Laser Marking Badge

Fast & powerful laser etching for a variety of surfaces

UV tablet sample of laser marking for pharmaceutical industry products
Ackley UV Laser Marking Badge

Precise & high-contrast marks for light colored surfaces

Cold & gentle laser for soft and sensitive surfaces


Let’s Rethink Ink Printing

Edible ink rotogravure printing methods have long been the standard for printing on consumable products. However, for some products, laser marking has significant benefits when compared to ink printing.

Benefits of Softgel Laser Marking

A Safe and Efficient Alternative

Our customers are often surprised to learn that soft gelatin capsules are durable enough to be laser marked.  In fact, laser marking is a safe and efficient alternative to ink printing that makes softgels stand out with a high quality, tamper-proof mark while minimizing operational costs and maintenance.


  • High Quality – Sharp, clean and permanent indelible mark
  • Reduced Operational Cost – Less clean up, maintenance and operator involvement
  • Flexibility – The size of the mark, or the mark itself, can easily be changed in the recipe
  • Durability – Mark on any surface

Can Softgels Be Laser Marked?

A Safe and Efficient Alternative

Our customers are often surprised to learn that soft gelatin capsules are durable enough to be laser marked. In fact, laser marking is a safe and efficient alternative with significant benefits compared to ink printing.

Learn More

Compliance

We adhere to or surpass the strictest regulations set forth by the Food and Drug Administration (FDA) and their approach to Current Good Manufacturing Practice (CGMP) regulations.

  • FDA 21 CFR Part 11 Compliant
  • cGMP Design
  • OPC-UA Data Compliant
  • Class 1 Laser System: FDA 21 CFR Part 1040
  • CE Compliant
  • Validation Package Available

Capsule and Tablet Laser Marking Machines

VIP Laser Drill + NIR Machine
CO2 Laser NIR Inspection Production R & D Vision Inspection

VIP Laser Drill + NIR

Drill & Inspect
View
Ackley Cantilever Ramp Laser Marking Machine
CO2 Laser Production UV Laser Vision Inspection

Cantilever Ramp Laser

Mark & Inspect
View
R&D Tablet Laser Drilling Machine
CO2 Laser R & D UV Laser

R&D Laser

Drill or Mark & Inspect
View
VIP Laser
CO2 Laser Production R & D Vision Inspection

VIP Laser

Drill or Mark & Inspect
View
Tablet Printing Machine - Drum Printer
CO2 Laser Production Vision Inspection

Servo Drum Laser Drill

Drill & Inspect
View

Get a FREE Product Evaluation

Need help figuring out the best machine for your product?

With a little information we can evaluate your product and help guide you to the right machine for printing, marking or laser drilling on your blank tablets and capsules.


Laser Marking Resources

Ask an Expert: Laser Marking and Alternative Wavelengths

Ask an Expert: Laser Marking and Alternative Wavelengths

From Star Wars to spectrometers, learn about optimizing your laser marker's throughput to meet production goals ...
Read the Article
Solid Dose Printing and Laser Marking

Ask an Expert: Applying Identification to Solid Dosage Drug Products

Learn the benefits and drawbacks of on-dose marking methods for solid dosage drug products—ink printing and CO2 / UV laser marking ...
Read the Article
The Evolution of the Printed Tablet & Capsule Whitepaper Cover

The Evolution of the Printed Tablet & Capsule

If you have ever dropped a tablet on the floor or mixed several pills of similar color together in a pill box, you understand how important it is to be ...
Get the Whitepaper


Other Capabilities

Seamless Laser Marking

Seamless Laser Marking

Ackley Capabilities - Laser Drilling Featured Image

Laser Drilling

Laser Marking Capabilities Featured Image

Laser Marking

Solid Dose Printing and Laser Marking

Capsule & Tablet Printing

Confectionery Printing

Confectionery Printing

NIR Inspection Osmotic Drug Delivery System Tablet Spill

NIR Inspection

Vision Inspection

Vision Inspection

Laser Drilling

Tablet and Capsule Laser Drilling Machines with Optional Vision Inspection

Today’s advanced osmotic tablet relies on the use of a small aperture created by a laser hole drilling machine. Through that precise hole, medications are released into the body at a controlled rate over time. These sub-millimeter sized microholes must be drilled to precisely the right size and position on the tablet or patient safety could be at risk. Ackley offers a full line of precision laser drilling systems, from small batch and R&D applications to full-scale production. Our lasers can accurately drill single or bi-layer tablets and feature a color recognition system to ensure the correct layer of the tablet is drilled every time. They can drill either single or multiple apertures, and allow users to store over 25 pre-programmed “recipes” making it easy to switch over between different products and pill sizes.  A user-friendly touchscreen interface allows for ease of operation and easy-to-swap carrier links and parts make changing between products quick and simple.

Our Ackley laser drilling systems are equipped with a vision inspection system to confirm the presence and diameter of each aperture with a single tablet rejection system to remove individual defective products. Additionally, we have integrated advanced NIR inspection technology into our laser hole drilling machines to create systems that perform automatic NIR inspection before tablet drilling and vision inspection occur. This optional NIR technology inspects the tablet at the near-infrared wavelength of light, to confirm the safety and integrity of the enteric coating for the osmotic tablet.  Whatever your laser drilling needs, Ackley’s engineering team is ready to design a solution that will give your brand a perfectly aligned, precisely drilled hole, each and every time.

  • Ackley Laser Drilling Tablet Samples 01
  • Ackley Laser Drilling Tablet Samples 02
  • Ackley Laser Drilling Tablet Samples 03
  • Ackley Laser Drilling Tablet Samples 04
  • Ackley Tablet Samples 05
  • Ackley Tablet Samples 06
  • Ackley Tablet Samples 07
  • Ackley Tablet Samples 08
  • Ackley Capabilities - Laser Drilling Featured Image

Compliance

We adhere to or surpass the strictest regulations set forth by the Food and Drug Administration (FDA) and their approach to Current Good Manufacturing Practice (CGMP) regulations.

  • FDA 21 CFR Part 11 Compliant
  • cGMP Design
  • OPC-UA Data Compliant
  • Class 1 Laser System: FDA 21 CFR Part 1040
  • CE Compliant
  • Validation Package Available

How Osmotic Drug Delivery Works

How Osmotic Drug Delivery Works Infographic

Laser Drilling Resources

Pharmaceutical Laser Drilling with NIR Inspection Whitepaper Cover

Pharmaceutical Laser Drilling with NIR Inspection

From sugar coatings to film and gel coatings, many types of outer coatings make tablets easier to swallow and protect from light and moisture infiltration. However, osmotic-controlled release oral delivery ...
Get the Whitepaper
VIP Laser Drill + NIR Machine

Ask an Expert: Near-infrared Inspection Systems

Learn what a near-infrared inspection (NIR) system is, how it works and what its benefits are for the pharmaceutical manufacturing industry ...
Read the Article
Laser Drilling Machine Ackley VIP

Generics Manufacturer Awaits Opportunity, Laser Drill at the Ready

Learn about a company that sought a pilot-scale system for laser drilling tablets to be ready for ANDA osmotic tablet opportunities ...
Read the Case Study

If you set it to drill just the yellow side of a bi-layer, it will, and it will reject the tablet if the side is another color.

– VP of R&D, West Coast Generic Pharmaceuticals Manufacturer

Laser Drilling Machines

VIP Laser Drill + NIR Machine
CO2 Laser NIR Inspection Production R & D Vision Inspection

VIP Laser Drill + NIR

Drill & Inspect
View
Ackley Cantilever Ramp Laser Marking Machine
CO2 Laser Production UV Laser Vision Inspection

Cantilever Ramp Laser

Mark & Inspect
View
R&D Tablet Laser Drilling Machine
CO2 Laser R & D UV Laser

R&D Laser

Drill or Mark & Inspect
View
VIP Laser
CO2 Laser Production R & D Vision Inspection

VIP Laser

Drill or Mark & Inspect
View
Tablet Printing Machine - Drum Printer
CO2 Laser Production Vision Inspection

Servo Drum Laser Drill

Drill & Inspect
View

Get a FREE Product Evaluation

Need help figuring out the best machine for your product?

With a little information we can evaluate your product and help guide you to the right machine for printing, marking or laser drilling on your blank tablets and capsules.


Other Capabilities

Seamless Laser Marking

Seamless Laser Marking

Ackley Capabilities - Laser Drilling Featured Image

Laser Drilling

Laser Marking Capabilities Featured Image

Laser Marking

Solid Dose Printing and Laser Marking

Capsule & Tablet Printing

Confectionery Printing

Confectionery Printing

NIR Inspection Osmotic Drug Delivery System Tablet Spill

NIR Inspection

Vision Inspection

Vision Inspection

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Pharmaceutical Printing Machines

  • VIP Printer
  • Adjustable Angle Ramp Printer
  • Cantilever Ramp Tablet and Capsule Printer
  • Servo Drum Printer

Laser Drilling & Marking Machines

  • VIP Laser Drill + NIR
  • VIP Laser
  • Cantilever Ramp Laser
  • R&D Laser
  • Servo Drum Laser Drill

Capabilities

  • Laser Drilling
  • Laser Marking
  • Capsule & Tablet Printing
  • Confectionery Printing
  • Vision Inspection
  • NIR Inspection

Industries We Serve

  • Pharmaceutical Manufacturing
  • Nutraceutical Industry
  • Confectionery Industry

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Ackley Machine Corp

Ackley The Leader in Pharmaceutical Printing, Laser Drilling and Vision Inspection Machinery
Copyright © 2025 Ackley Machine Corporation • 1273 North Church St. #106, Moorestown, NJ 08057 • (856) 234-3626

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